Hubungan Tingkat Kepatuhan Terapi Antihipertensi Dengan Kualitas Hidup Pasien Di Puskesmas Kota Padang
Abstract
Hypertension is a condition diagnosed when repeated blood pressure measurements show values ≥140/90 mmHg. Long-term treatment is required to control blood pressure, making patient adherence to therapy essential for achieving therapeutic targets. Non-adherence can negatively impact patients’ quality of life, as poor health-related quality of life may limit daily functioning. The Pill Count method and the SF-36 questionnaire were used to assess medication adherence and quality of life. This study aimed to determine the relationship between antihypertensive medication adherence and the quality of life in hypertensive patients. The research was conducted at Lubuk Buaya Public Health Center from February to March 2023. It was a non-experimental analytic study using a cross-sectional method. A total of 90 participants were selected using purposive sampling. The results showed that adherence to antihypertensive medication significantly influenced only certain domains, likely due to most respondents exhibiting good adherence and high awareness, which contributed to a better quality of life. Chi-square analysis revealed a significant relationship between medication adherence and health-related quality of life, particularly in the domains of bodily pain, social functioning, and mental health.
Downloads
References
Indonesia PDS kardiovaskular. Pedoman Tatalaksana Hipertensi Pada Penyakit Kardiovaskular. Jakarta: PERKI; 2015.
Perhimpunan Dokter Hipertensi Indonesia (PERHI). Konsensus Penatalaksanaan Hipertensi 2019. Indones Soc Hipertens Indones. 2019;1–90.
Padang DK. Profil Kesehatan Kota Padang Tahun 2021. 2021.
Ghufron Mukti A. Optimalisasi dan pengelolaan penyakit kronis selama pandemi covid-19. BPJS Kesehat. 2021;3.
Sami’un, Pertiwi AD, Rahmawati S. Evaluasi Ketepatan Obat Anti Hipertensi Pada Pasien Rawat Abstrak Evaluation of Anti-Hypertension Precision on Outpatient. J Farmasetis. 2018;7(1):23–32.
Ernawati I, Lubada EI, Lusiyani R, Prasetya RA. Association of adherence measured by self-reported pill count with achieved blood pressure level in hypertension patients: a cross-sectional study. Clin Hypertens. 2022;28(1):1–6.
Warnidah H, Helmidanora R, Sentat T, Sukawaty Y, Handayani E. Profil Kepatuhan Minum Obat Pada Pasien Hipertensi Di Puskesmas Muara Wis. Ahmar Metastasis Heal J. 2021;1(3):118–23.
Bakas T, McLennon SM, Carpenter JS, Buelow JM, Otte JL, Hanna KM, et al. Systematic review of health-related quality of life models. Health Qual Life Outcomes [Internet]. 2012;10(1):1. Tersedia pada: Health and Quality of Life Outcomes
Afiani N. Analisis Determinan Kualitas Hidup Pada Pasien Dengan Hipertensi Derajat II. J Ilm Kesehat Media Husada. 2014;3(1):1–14.
Uchmanowicz B, Chudiak A, Mazur G. The influence of quality of life on the level of adherence to therapeutic recommendations among elderly hypertensive patients. Patient Prefer Adherence. 2018;12:2593–603.
Xiao M, Zhang F, Xiao N, Bu X, Tang X, Long Q. Health-related quality of life of hypertension patients: A population-based cross-sectional study in Chongqing, China. Int J Environ Res Public Health. 2019;16(13).
Abdiana. Kualitas Hidup Penderita Penyakit Hipertensi Peserta Prolanis Di Puskesmas Kecamatan Padang Utara Kota Padang. J Sehat Mandiri. 2019;14(2):38–47.
Rachmawati Y, Perwitasari DA, Adnan. Validasi Kuesioner Sf-36 Versi Indonesia. Pharmacy [Internet]. 2014;11(01):14–25.
Grymonpre RE, Didur CD, Montgomery PR, Sitar DS. Pill count, self-report, and pharmacy claims data to measure medication adherence in the elderly. Ann Pharmacother. 1998;32(7–8):749–54.
Setiani LA, Almasyhuri, Hidayat AA. Evaluasi Kepatuhan Pasien Pada Penggunaan Obat Antidiabetik Oral Dengan Metode Pill-Count dan MMAS-8 Di Rumah Sakit PMI Kota Bogor. J Ilm Ilmu Terap Univ Jambi. 2022;6(1):32–46.
Priantoro H. Hubungan Beban Kerja Dan Lingkungan Kerja Dengan Kejadian Burnout Perawat Dalam Menangani Pasien Bpjs. J Ilm Kesehat. 2018;16(3):9–16.
Wang, J., Zhang, L., Wang, F., Liu, L., & Wang, H. (2020). Prevalence, awareness, treatment, and control of hypertension in China: Results from a national survey. Journal of Hypertension, 38(3), 305-317.
Gupta, R., Xavier, D., & Roy, A. (2019). Hypertension prevalence and blood pressure trends in India: A systematic review. Journal of Human Hypertension, 33(6), 575-587.
Williams, B., Mancia, G., Spiering, W., et al. (2018). 2018 ESC/ESH Guidelines for the management of arterial hypertension. European Heart Journal, 39(33), 3021-3104.
Vrijens, B., Antoniou, S., Burnier, M., de la Sierra, A., & Volpe, M. (2017). Current situation of medication adherence in hypertension. Frontiers in Pharmacology, 8, 100.
Burnier, M., & Egan, B. M. (2019). Adherence in hypertension: A review of prevalence, risk factors, impact, and management. Circulation Research, 124(7), 1124-1140.
Harahap DA, Aprilla N, Muliati O. Hubungan Pengetahuan Penderita Hipertensi Tentang Hipertensi Dengan Kepatuhan Minum Obat Antihipertensi Di Wilayah Kerja Puskesmas Kampa Tahun 2019. J Ners [Internet]. 2019;3(2):97–102.
Cahyani FM. Hubungan Kepatuhan Minum Obat Antihipertensi Terhadap Tercapainya Target Terapi Pasien Hipertensi di Puskesmas Wirobrajan Yogyakarta. J Pharm Sci Med Res. 2018;1(2):10.
Nurmalita V, Annisaa E, Pramono D, Sunarsih ES. Hubungan Kepatuhan Minum Obat Antihipertensi Terhadap Kualitas Hidup Pada Pasien Hipertensi. 2019;8(4):1366–74.
Wahyudi C, Ratnawati D, Made S. Pengaruh Demografi, Psikososial, Dan Lama Menderita Hipertensi Primer Terhadap Kepatuhan Minum Obat Antihipertensi. J JKFT. 2018;2(2):14.
Nurmalita V, Annisaa E, Pramono D, Sunarsih E. Hubungan Kepatuhan Minum Obat Antihipertensi Terhadap Kualitas Hidup Pada Pasien Hipertensi. 2019;8(4):1366–74
Lima J, Mion D, Pierin A. Health Related Quality Of Life And Blood Pressure Control In Hypertensive Patients With Complications. 2009;64(7):619–28. And Without Clinics. [23]
Anbarasan, S. Gambaran Kualitas Hidup Lansia Dengan Hipertensi Di Wilayah Kerja Puskesmas Rendang Pada Periode 27 Februari Sampai 14 Maret 2015. Intisari Sains Medis. 2015;113–2
Kretchy I, Owusu-Daaku F, Danquah S. Mental health in hypertension: Assessing symptoms of anxiety, depression and stress on anti hypertensive medication adherence. Int J Mental Health System. 2014;8(1):1–6.

This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under an Attribution 4.0 International (CC BY 4.0) that allows others to share — copy and redistribute the material in any medium or format and adapt — remix, transform, and build upon the material for any purpose, even commercially with an acknowledgment of the work's authorship and initial publication in this journal.













